Health and Beauty

asthma prognosis

May 2019: Extramural Papers of the Month

DNA polymerase theta protects against UV-induced cancer

NIEHS grantees provided evidence that the enzyme DNA polymerase theta (pol Q) protects against skin cancer induced by ultraviolet (UV) light, although pol Q also increases the number of UV-induced mutations. They observed that pol Q might play a protective role through a process called error-prone translesion synthesis (TLS), which allows DNA to replicate past mutations and tolerate DNA damage.

To understand the role of TLS in skin cancer formation, the researchers used cell studies to analyze the enzymes that synthesize DNA molecules, known as DNA polymerases, to determine which DNA polymerase is responsible for generating UV-induced mutations. In cell studies, they showed that pol Q led to an increase in mutations induced by UV exposure and was required to generate certain types of mutations.

Because pol Q led to DNA mutations in cells, the scientists generated a pol Q-deficient mouse model and examined susceptibility to UV-induced skin cancers. Contrary to expectations, the team found that pol Q-deficient mice were more susceptible to skin cancer from UV damage.

what is the prognosis for someone who has asthma ?

they can live a normal life as long as they careful of there environment is s dust , pollen , sprays an any thing else they can up set there condition .. just carry a inhaler and enjoy life /yes it will be different but still can be full of enjoyme

What can I do if I do not agree with a Doctors prognosis?

I recently went to my doctors and they told me I have asthma but I do not agree, I have had a chest infection and that's all. Can I see another doctor or will that insult my GP and cause future problems for me? Hope anyone can help, Thank you

You can alway see another doc. It should not offend them. That is life. You are the consumer. They are offering you a services. You shop around for insurance, cars etc. YOu should shop around for a good doc that you trust.


That's not a prognosis. That's a diagnosis. A prognosis is a forecast of how the condition is likely to behave.

I've little doubt that your doctor may feel that you have 'insulted' him by seeking a second opinion, but it's your health

You have the right to see another doctor for a second opinion. If the second doctor says the same I would tend to think they're right and you're wrong though.

Doctors often make mistakes. They're human too.

I think any decent