Health and Beauty

Osteoporosis En Espanol

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    Osteoporosis: Terapias Naturales Para La Curacion Integral / Natural Therapies for Holistic Healing (Spanish Edition) (Guia De Consulta Y Prevencion / Consultation and Prevention Guide)
    Book (Downtown Book Center)

    Downtown Book Center

    List Price: $14.99

    Acefit Exercise Ball - Professional Grade Anti-Burst Yoga Fitness, Balance Ball for Pilates, Yoga, Stability Training and Physical Therapy Yoga Ball for Women and Men outdoor fitness ball Green 45 CM
    Sports (Acefit)


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A closer look at osteoporosis medication's mechanisms may ...

Osteoporosis is the primary cause of bone fractures in the elderly. Bone loss in this disease reflects an imbalance between the activity of bone-degrading cells called osteoclasts and bone-building cells called osteoblasts. Teriparatide, a recombinant form of parathyroid hormone, is currently the only FDA-approved treatment for osteoporosis that targets bone formation. This medication stimulates osteoblast activity and increases the lifespan of osteoblasts, but whether it also enhances the production of these bone-forming cells is unknown.

New findings from Henry Kronenberg's lab at Massachusetts General Hospital and Harvard Medical School suggest that while teriperatide treatment does increase the proliferation of osteoblasts, stopping treatment may have adverse effects. A study published this week in the JCI reports that the number of osteoblast precursor cells and their mature descendants increased in mice undergoing teriparatide treatment. When mice were withdrawn from teriparatide treatment, not only did osteoblast proliferation diminish, but the number of newly-formed fat cells, or adipocytes, increased.