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Asthma Xanthine

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    Anti-asthma Xanthines and Adenosine: Symposium Proceedings (Current clinical practice series)
    Book (Elsevier Science Ltd)

    Price: $49.95

Improving Lung Function (FEV1) in COPD Through Appropriate Counseling on Use of Inhaled Medications

DRUG INTERACTIONS Use caution if administering adrenergic drugs because sympathetic effects of olodaterol may be potentiated. Concomitant treatment with xanthine derivatives, steroids, or diuretics may potentiate any hypokalemic effect of olodaterol. Beta agonists, such as olodaterol, can acutely worsen the ECG changes and/or hypokalemia that may result from administration of non-potassium sparing diuretics. The action of adrenergic agents on the cardiovascular system may be potentiated by monoamine oxidase inhibitors or tricyclic antidepressants or other drugs known to prolong the QTc interval. Therefore beta-agonists should be used with extreme caution in patients being treated with these drugs. Drugs that prolong the QTc interval may be associated with an increased risk of ventricular arrhythmias. Beta-blockers should be used with caution as they can inhibit the therapeutic effect of beta agonists which may produce severe bronchospasms in patients with COPD. However,